Using An Esterification Reaction And Conduct A Purity Test...

Objective: Students will be able to synthesize aspirin using an esterification reaction and conduct a purity test on the aspirin crystals and a commercial aspirin product. Procedure: Preparation of Aspirin- Begin by weighing a 125-mL Erlenmeyer flask and recording the result. Next, add approximately 2 g of salicylic acid to the Erlenmeyer flask. Then, record the new mass of the Erlenmeyer and the salicylic acid. Next, inside of the hood add 5 mL of acetic anhydride and 10 drops of 85% phosphoric acid. Stir the mixture with a stirring rod. Next, place the flask in a boiling water bath and stir until the solid dissolves. Next, remove the flask from the water bath and let it cool to room temperature. Then, add 20 drops of water to the flask. Next, add 25-mL of cold water to the flask and place it in an ice bath for 10 minutes. After 10 minutes, to collect the Aspirin crystals, add a piece of filter paper to a BÃ ¼chner filtration apparatus. Then, fit the funnel snuggly in the rubber washer of the filter flask. Next, turn on the water aspirator and pour the aspirin product slowly onto the center of the filter paper. Then, push down gently on the funnel to suction out the water from the asp irin product. After the crystals have formed on the filter paper, obtain a weight boat. Record the mass of the weight boat. Next, use a spatula to transfer the crystals onto the weigh boat. Then, after the crystals have dried, record the mass of the weight boat and aspirin product. Testing